The test article, Booster Gel Lot 70710-D and Daywhite 15% Lot 970701, Lot #70710-D & Lot A 970701, was evaluated for the potential to cause irritation to the mucosal tissue in the cheek of the rat. In each of seven rats, the test article was repeatedly swabbed across the mucosal tissue of the cheek over the course of 14 days. For a basis of comparison, five animals were similarly treated with Municipal Water as a negative control. Animals were observed daily for general health and on treatment days and at termination for macroscopic signs of mucosal damage and angular cheilitis. A final examination was conducted 1 day following the last treatment.

Under the conditions of this study, the test article was not considered to be irritating to the cheek of the rat. The death of the one test animal was not believed to be caused by the administration of the test article mixture.


CONCLUSION


Under the conditions of this study, the test article was not considered to be irritating to the cheek of the rat. The death of the one test animal was not believed to be caused by the administration of the administration of the test article mixture.